Cholesterol, Atherosclerosis, and APOE in Vascular Contributions to Cognitive Impairment and Dementia (VCID): Potential Mechanisms and Therapy

Cholesterol, Atherosclerosis, and APOE in Vascular Contributions to Cognitive Impairment and Dementia (VCID): Potential Mechanisms and Therapy

Vascular contributions to cognitive impairment and dementia (VCID) are a common cause of cognitive decline, yet limited therapies exist. This cerebrovascular disease results in neurodegeneration via acute, chronic, local, and systemic mechanisms. The etiology of VCID is complex, with a significant i...

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Bibliographic Details
Main Authors: Michael Tran Duong, Ilya M. Nasrallah, David A. Wolk, Catherine C. Y. Chang, Ta-Yuan Chang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Aging Neuroscience
Subjects:
cholesterol
atherosclerosis
APOE
vascular dementia
inflammation
glia
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2021.647990/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2021.647990/full

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