Structural transitions during the scaffolding-driven assembly of a viral capsid

Viral assembly is a complex process that in tailed bacteriophages involves scaffolding proteins which coordinate assembly of the phage procapsid and are subsequently released during maturation. Here the authors reveal the conformational changes that accompany virion maturation, documenting how the d...

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Bibliographic Details
Main Authors: Athanasios Ignatiou, Sandrine Brasilès, Mehdi El Sadek Fadel, Jörg Bürger, Thorsten Mielke, Maya Topf, Paulo Tavares, Elena V. Orlova
Format: Article
Language:English
Published: Nature Publishing Group 2019-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-12790-6