Genetic variants in nuclear DNA along with environmental factors modify mitochondrial DNA copy number: a population-based exome-wide association study

Genetic variants in nuclear DNA along with environmental factors modify mitochondrial DNA copy number: a population-based exome-wide association study

Abstract Background Mitochondrial DNA (mtDNA) copy number has been found associated with multiple diseases, including cancers, diabetes and so on. Both environmental and genetic factors could affect the copy number of mtDNA. However, limited study was available about the relationship between genetic...

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Bibliographic Details
Main Authors: Zhihua Li, Meng Zhu, Jiangbo Du, Hongxia Ma, Guangfu Jin, Juncheng Dai
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Genomics
Subjects:
MtDNA copy number
Genetic variants
Exome-wide association study
PM2.5 exposure
Online Access:http://link.springer.com/article/10.1186/s12864-018-5142-7

Internet

http://link.springer.com/article/10.1186/s12864-018-5142-7

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