Astrocytes Are More Resistant Than Neurons to the Cytotoxic Effects of Increased [Zn2+]i
Increased intracellular free Zn2+ ([Zn2+]i) is toxic to neurons. Glia are more resistant to Zn2+-mediated toxicity; however, it is not known if this is because glia are less permeable to Zn2+ or if glia possess intrinsic mechanisms that serve to buffer or extrude excess [Zn2+]i. We used the Zn2+-sel...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2000-08-01
|
Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996100903036 |