Role of the RAGE Axis during the Immune Response after Severe Trauma: A Prospective Pilot Study

Background. Severe traumatization induces a complex pathophysiology, driven by the patient’s own immune system. The initial activation is a result of damage-associated molecular patterns, which are released from disrupted and dying cells and recognized by immune receptors, for example, RAGE. In this...

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Bibliographic Details
Main Authors: Florian Uhle, Christoph Lichtenstern, Thorsten Brenner, Thomas Fleming, Christian Koch, Andreas Hecker, Christian Heiss, Peter Paul Nawroth, Stefan Hofer, Markus Alexander Weigand, Katja Weismüller
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2015/691491