Structurally unique PARP‐1 inhibitors for the treatment of prostate cancer

Abstract The prognosis for metastatic castration‐resistant prostate cancer is unfavorable, and although Poly(ADP)‐ribose polymerase‐1 (PARP‐1) inhibitors have shown efficacy in the treatment of androgen‐receptor dependent malignancies, the limited number of options present obstacles for patients tha...

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Bibliographic Details
Main Authors: Ali Divan, Mukund P. Sibi, Alexei Tulin
Format: Article
Language:English
Published: Wiley 2020-04-01
Series:Pharmacology Research & Perspectives
Subjects:
Online Access:https://doi.org/10.1002/prp2.586