Sodium-Dependent Glucose Transporter 1 (SGLT1) Stabled by HER2 Promotes Breast Cancer Cell Proliferation by Activation of the PI3K/Akt/mTOR Signaling Pathway in HER2+ Breast Cancer

Aerobic glycolysis is a hallmark of tumor cells. SGLT1 plays a vital role in glucose metabolism. However, whether SGLT1 could promote cell growth and proliferation in breast cancer remains unclear. Here, we investigated the expression of SGLT1 in breast cancer and examined its role in malignant beha...

Full description

Bibliographic Details
Main Authors: Jinlu Wang, Hongfei Ji, Xingjian Niu, Lei Yin, Yiran Wang, Yucui Gu, Dongbo Li, Han Zhang, Minghui Lu, Fengxia Zhang, Qingyuan Zhang
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2020/6103542