Exosomes from primed MSCs can educate monocytes as a cellular therapy for hematopoietic acute radiation syndrome

Exosomes from primed MSCs can educate monocytes as a cellular therapy for hematopoietic acute radiation syndrome

Abstract Background Acute radiation syndrome (ARS) is caused by acute exposure to ionizing radiation that damages multiple organ systems but especially the bone marrow (BM). We have previously shown that human macrophages educated with exosomes from human BM-derived mesenchymal stromal cells (MSCs)...

Full description

Bibliographic Details
Main Authors: Matthew H. Forsberg, John A. Kink, Anna S. Thickens, Bryson M. Lewis, Charlie J. Childs, Peiman Hematti, Christian M. Capitini
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem cells
Exosomes
Monocytes
Lipopolysaccharide
Acute radiation syndrome
Hematopoiesis
Online Access:https://doi.org/10.1186/s13287-021-02491-7

Internet

https://doi.org/10.1186/s13287-021-02491-7

Similar Items