Synthesis and Cytotoxicity of Thieno[2,3-b]Pyridine Derivatives Toward Sensitive and Multidrug-Resistant Leukemia Cells

Synthesis and Cytotoxicity of Thieno[2,3-b]Pyridine Derivatives Toward Sensitive and Multidrug-Resistant Leukemia Cells

A new series of substituted ethyl 7-cyclopropyl-2-(2-aryloxo)-3-nitro-4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxylates 3a–e were prepared by utilizing ethyl 2-chloro-7-cyclopropyl-3-nitro-4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxylate (1) and replacing of the 2-chlorine with anions obtain...

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Bibliographic Details
Main Authors: Salah A. Al-Trawneh, Amer H. Tarawneh, Anastassiya V. Gadetskaya, Ean-Jeong Seo, Mohammad R. Al-Ta’ani, Samir A. Al-Taweel, Mustafa M. El-Abadelah
Format: Article
Language:English
Published: Slovenian Chemical Society 2021-06-01
Series:Acta Chimica Slovenica
Subjects:
thieno[2,3-b]pyridine
multidrug resistance
cytotoxicity.
Online Access:https://journals.matheo.si/index.php/ACSi/article/view/6609

Internet

https://journals.matheo.si/index.php/ACSi/article/view/6609

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