Non-classical Protein Excretion Is Boosted by PSMα-Induced Cell Leakage

Non-classical Protein Excretion Is Boosted by PSMα-Induced Cell Leakage

Release of cytoplasmic proteins into the supernatant occurs both in bacteria and eukaryotes. Because the underlying mechanism remains unclear, the excretion of cytoplasmic proteins (ECP) has been referred to as “non-classical protein secretion.” We show that none of the known specific protein transp...

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Bibliographic Details
Main Authors: Patrick Ebner, Arif Luqman, Sebastian Reichert, Ksenia Hauf, Peter Popella, Karl Forchhammer, Michael Otto, Friedrich Götz
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Cell Reports
Subjects:
cytoplasmic proteins
membrane damage
non-classical protein secretion
phenol-soluble-modulins
Staphylococcus aureus
aldolase
enolase
GAPDH
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717310240

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http://www.sciencedirect.com/science/article/pii/S2211124717310240

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