Assessments of the accumulation severities of amyloid β-protein and hyperphosphorylated tau in the medial temporal cortex of control and Alzheimer's brains

Alzheimer's disease (AD) is characterized neuropathologically by neuritic plaques (NPs), and neurofibrillary tangles (NFTs). So far, the following key issues are not yet answered to the disease: (1) the accumulation degrees of three Aβ variants, and tau phosphorylation epitopes in AD as compare...

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Bibliographic Details
Main Authors: Xin-Wen Zhou, Xu Li, Cecilia Bjorkdahl, Magnus J. Sjogren, Irina Alafuzoff, Hilkka Soininen, Inge Grundke-Iqbal, Khalid Iqbal, Bengt Winblad, Jin-Jing Pei
Format: Article
Language:English
Published: Elsevier 2006-06-01
Series:Neurobiology of Disease
Subjects:
Tau
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996106000088