Novel liquid-liquid extraction and self-emulsion methods for simplified isolation of extra-virgin olive oil phenolics with emphasis on (-)-oleocanthal and its oral anti-breast cancer activity.

Epidemiological and clinical studies compellingly documented the ability of Mediterranean diet rich in extra-virgin olive oil (EVOO) to reduce breast and colon cancers incidence, cardiovascular diseases, and aging cognitive functions decline. (-)-Oleocanthal (OC) and other EVOO phenolics gain progre...

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Bibliographic Details
Main Authors: Abu Bakar Siddique, Hassan Ebrahim, Mohamed Mohyeldin, Mohammed Qusa, Yazan Batarseh, Ahmed Fayyad, Afsana Tajmim, Sami Nazzal, Amal Kaddoumi, Khalid El Sayed
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0214798