Universal Architectural Concepts Underlying Protein Folding Patterns

Universal Architectural Concepts Underlying Protein Folding Patterns

What is the architectural “basis set” of the observed universe of protein structures? Using information-theoretic inference, we answer this question with a dictionary of 1,493 substructures—called concepts—typically at a subdomain level, based on an unbiased subset of known protein structures. Each...

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Bibliographic Details
Main Authors: Arun S. Konagurthu, Ramanan Subramanian, Lloyd Allison, David Abramson, Peter J. Stuckey, Maria Garcia de la Banda, Arthur M. Lesk
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Molecular Biosciences
Subjects:
architectural concepts
protein-building blocks
structural motifs
lossless compression
information theory
folding pattern
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2020.612920/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2020.612920/full

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