Investigation of the Optimal Dose aPCC in Reversing the Effect of Factor Xa Inhibitors—An In Vitro Study

Factor (F) Xa inhibitors are safe and effective alternatives to warfarin. There are concerns about the lack of a reversal strategy in case of serious bleeds or need for emergency surgery in situations when the antidote andexanet alfa is not available. Factor concentrates are widely used, but there a...

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Bibliographic Details
Main Authors: Nina Haagenrud Schultz MD, PhD, Jawed Fareed DSc, PhD, Pål Andre Holme MD, PhD
Format: Article
Language:English
Published: SAGE Publishing 2021-05-01
Series:Clinical and Applied Thrombosis/Hemostasis
Online Access:https://doi.org/10.1177/10760296211021156