Effect of infliximab on the levels of TNF-alpha and TGF-beta in the whole blood cultures of irradiated patients.
TGF-beta is supposed to be the major cytokine responsible for post-radiation fibrosis of healthy tissues and actively modifies post-radiation changes. The growth of TGF-beta level induces the expression of collagen synthesis gene which triggers off the production of fibrosis of hyaline membranes. Th...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Via Medica
2008-12-01
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| Series: | Folia Histochemica et Cytobiologica |
| Online Access: | http://czasopisma.viamedica.pl/fhc/article/view/4421 |