Effect of infliximab on the levels of TNF-alpha and TGF-beta in the whole blood cultures of irradiated patients.
TGF-beta is supposed to be the major cytokine responsible for post-radiation fibrosis of healthy tissues and actively modifies post-radiation changes. The growth of TGF-beta level induces the expression of collagen synthesis gene which triggers off the production of fibrosis of hyaline membranes. Th...
Main Authors: | Agnieszka Magrys, Helena Donica, Maria Koziol-Montewka, Krzysztof J Czarnocki, Elzbieta Staroslawska |
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Format: | Article |
Language: | English |
Published: |
Via Medica
2008-12-01
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Series: | Folia Histochemica et Cytobiologica |
Online Access: | http://czasopisma.viamedica.pl/fhc/article/view/4421 |
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