Targeting Endothelial Barrier Dysfunction Caused by Circulating Bacterial and Mitochondrial N-Formyl Peptides With Deformylase

Targeting Endothelial Barrier Dysfunction Caused by Circulating Bacterial and Mitochondrial N-Formyl Peptides With Deformylase

Despite recent advances in our understanding of the mechanisms underlying systemic inflammatory response syndrome (SIRS) and sepsis, the current therapeutic approach to these critically ill patients is centered around supportive care including fluid resuscitation, vasopressors and source control. Th...

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Bibliographic Details
Main Authors: Patricia Martinez-Quinones, Amel Komic, Cameron G. McCarthy, R. Clinton Webb, Camilla Ferreira Wenceslau
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Immunology
Subjects:
sepsis
SIRS
trauma
DAMPs
formyl peptide receptor-1
deformylase
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01270/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01270/full

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