Standardization of the Filovirus Plaque Assay for Use in Preclinical Studies

Standardization of the Filovirus Plaque Assay for Use in Preclinical Studies

The filovirus plaque assay serves as the assay of choice to measure infectious virus in a cell culture, blood, or homogenized tissue sample. It has been in use for more than 30 years and is the generally accepted assay used to titrate virus in samples from animals treated with a potential antiviral...

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Bibliographic Details
Main Authors: Gene G. Olinger, Ana Kuehne, Jennifer L. Audet, Kendra J. Alfson, Anthony Griffiths, Holly A. Bloomfield, Elizabeth E. Zumbrun, Ashley E. Keeney, Julia E. Biggins, Amy C. Shurtleff, Sina Bavari
Format: Article
Language:English
Published: MDPI AG 2012-12-01
Series:Viruses
Subjects:
plaque assay
filovirus
Ebola
ebolavirus
marburgvirus
Marburg virus
Vero
Online Access:http://www.mdpi.com/1999-4915/4/12/3511

Internet

http://www.mdpi.com/1999-4915/4/12/3511

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