Tumor-derived microvesicles induce proangiogenic phenotype in endothelial cells via endocytosis.

Increasing evidence indicates that tumor endothelial cells (TEC) differ from normal endothelial cells (NEC). Our previous reports also showed that TEC were different from NEC. For example, TEC have chromosomal abnormality and proangiogenic properties such as high motility and proliferative activity....

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Main Authors: Taisuke Kawamoto, Noritaka Ohga, Kosuke Akiyama, Naoya Hirata, Shuji Kitahara, Nako Maishi, Takahiro Osawa, Kazuyuki Yamamoto, Miyako Kondoh, Masanobu Shindoh, Yasuhiro Hida, Kyoko Hida
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3316594?pdf=render