Isolation and characterization of malaria PfHRP2 specific VNAR antibody fragments from immunized shark phage display library

Abstract Background Malaria rapid diagnostic tests (RDTs) represent an important antibody based immunoassay platform. Unfortunately, conventional monoclonal antibodies are subject to degradation shortening shelf lives of RDTs. The variable region of the receptor (VNAR) from shark has a potential as...

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Bibliographic Details
Main Authors: Chiuan Herng Leow, Katja Fischer, Chiuan Yee Leow, Katleen Braet, Qin Cheng, James McCarthy
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Malaria Journal
Online Access:http://link.springer.com/article/10.1186/s12936-018-2531-y