Multiple independent origins of a protease inhibitor resistance mutation in salvage therapy patients

<p>Abstract</p> <p>Background</p> <p>Combination anti-viral therapies have reduced treatment failure rates by requiring multiple specific mutations to be selected on the same viral genome to impart high-level drug resistance. To determine if the common protease inhibito...

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Bibliographic Details
Main Authors: Shulman Nancy, Shafer Robert W, Shapiro Beth, Kapoor Amit, Rhee Soo-Yon, Delwart Eric L
Format: Article
Language:English
Published: BMC 2008-01-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/5/1/7