Improved RNA quality and TaqMan<sup>® </sup>Pre-amplification method (PreAmp) to enhance expression analysis from formalin fixed paraffin embedded (FFPE) materials

<p>Abstract</p> <p>Background</p> <p>Archival formalin-fixed paraffin-embedded (FFPE) tissues represent an abundant source of clinical specimens; however their use is limited in applications involving analysis of gene expression due to RNA degradation and modification d...

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Bibliographic Details
Main Authors: Pirotta Marco, Aherne Sinead, Flavin Richard, Denning Karen, Cahill Susanne, Smyth Paul, Li Jinghuan, Guenther Simone M, O'Leary John J, Sheils Orla
Format: Article
Language:English
Published: BMC 2008-02-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/8/10