USP1 Regulates TAZ Protein Stability Through Ubiquitin Modifications in Breast Cancer
The Hippo signaling pathway is an evolutionarily conserved pathway that was initially discovered in <i>Drosophila melanogaster </i>and was later found to have mammalian orthologues. The key effector proteins in this pathway, YAP/TAZ, are often dysregulated in cancer, leading to a high de...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-10-01
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Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/12/11/3090 |