Hierarchical assembly of centriole subdistal appendages via centrosome binding proteins CCDC120 and CCDC68

Hierarchical assembly of centriole subdistal appendages via centrosome binding proteins CCDC120 and CCDC68

Centriole subdistal appendages (SDAs) anchor microtubules in interphase cells, but their composition and assembly mechanisms are unclear. Here the authors show that two new SDA components, CCDC120 and CCDC68, are required for hierarchical SDA assembly and centrosome microtubule anchoring.

Bibliographic Details
Main Authors: Ning Huang, Yuqing Xia, Donghui Zhang, Song Wang, Yitian Bao, Runsheng He, Junlin Teng, Jianguo Chen
Format: Article
Language:English
Published: Nature Publishing Group 2017-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms15057

Internet

https://doi.org/10.1038/ncomms15057

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