Identification of phosphodiesterase-4 as the therapeutic target of arctigenin in alleviating psoriatic skin inflammation

Identification of phosphodiesterase-4 as the therapeutic target of arctigenin in alleviating psoriatic skin inflammation

Introduction: Arctigenin, derived from Arctium lappa L., has multiple pharmacological activities, including immunoregulatory, anti-diabetic, anti-tumor, and neuroprotective effects. Nevertheless, the potential therapeutic target of arctigenin in modulating inflammation remains undefined. Objectives:...

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Bibliographic Details
Main Authors: Heng Li, Xianglei Zhang, Caigui Xiang, Chunlan Feng, Chen Fan, Moting Liu, Huimin Lu, Haixia Su, Yu Zhou, Qing Qi, Yechun Xu, Wei Tang
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Journal of Advanced Research
Subjects:
PDE4
Arctigenin
Psoriasis
Inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123221000321

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http://www.sciencedirect.com/science/article/pii/S2090123221000321

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