A rare co-segregation-mutation in the insulin receptor substrate 1 gene in one Chinese family with ankylosing spondylitis.

A rare co-segregation-mutation in the insulin receptor substrate 1 gene in one Chinese family with ankylosing spondylitis.

Ankylosing spondylitis (AS; MIM 106300) is a common rheumatic disease with strong genetic components affecting approximately 0.3% of the population. The exact genetic mechanism of AS remains elusive. Our previous study showed that AS could be transmitted in an autosomal dominant inheritance mode and...

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Bibliographic Details
Main Authors: Ju Rong, Qiuxia Li, Pingping Zhang, Xinyu Wu, Jinxian Huang, Chao Li, Zetao Liao, Yingying Xie, Qing Lv, Qiujing Wei, Tianwang Li, Jianlin Huang, Shuangyan Cao, Yan Shen, Jieruo Gu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4433214?pdf=render

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http://europepmc.org/articles/PMC4433214?pdf=render

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