Nidogen-1 Degraded by Cathepsin S can be Quantified in Serum and is Associated with Non–Small Cell Lung Cancer
Loss of basement membrane (BM) integrity is typically associated with cancer. Nidogen-1 is an essential component of the BM. Nidogen-1 is a substrate for cathepsin-S (CatS) which is released into the tumor microenvironment. Measuring nidogen-1 degraded by CatS may therefore have biomarker potential...
Main Authors: | Nicholas Willumsen, Cecilie L. Bager, Diana J. Leeming, Anne-Christine Bay-Jensen, Morten A. Karsdal |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2017-04-01
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Series: | Neoplasia: An International Journal for Oncology Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1476558616302342 |
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