Cellular and Molecular Changes of Brain Metastases-Associated Myeloid Cells during Disease Progression and Therapeutic Response

Cellular and Molecular Changes of Brain Metastases-Associated Myeloid Cells during Disease Progression and Therapeutic Response

Summary: Brain-resident microglia and bone marrow-derived macrophages represent the most abundant non-cancerous cells in the brain tumor microenvironment with critical functions in disease progression and therapeutic response. To date little is known about genetic programs that drive disease-associa...

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Bibliographic Details
Main Authors: Michael Schulz, Birgitta Michels, Katja Niesel, Stefan Stein, Henner Farin, Franz Rödel, Lisa Sevenich
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:iScience
Subjects:
Immunology
Systems Biology
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220303631

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http://www.sciencedirect.com/science/article/pii/S2589004220303631

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