Lymphocytes with Cytotoxic Activity Induce Rapid Microtubule Axonal Destabilization Independently and before Signs of Neuronal Death

MS (multiple sclerosis) is the most prevalent autoimmune disease of the CNS (central nervous system) historically characterized as an inflammatory and demyelinating disease. More recently, extensive neuronal pathology has lead to its classification as a neurodegenerative disease as well. While the i...

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Bibliographic Details
Main Authors: Nichole M. Miller, Leah P. Shriver, Vijaya L. Bodiga, Avijit Ray, Sreemanti Basu, Rajiv Ahuja, Arundhati Jana, Kalipada Pahan, Bonnie N. Dittel
Format: Article
Language:English
Published: SAGE Publishing 2013-01-01
Series:ASN Neuro
Online Access:https://doi.org/10.1042/AN20120087