Rapamycin-loaded nanoparticles for inhibition of neointimal hyperplasia in experimental vein grafts

<p>Abstract</p> <p>Background</p> <p>Nanoparticles possess several advantages as a carrier system for intracellular delivery of therapeutic agents. Rapamycin is an immunosuppressive agent which also exhibits marked antiproliferative properties. We investigated whether r...

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Bibliographic Details
Main Authors: Ma Hao, Zhu Yi, Yang Hongyu, Zhang Xiwei, Zou Junjie, Wang Shui
Format: Article
Language:English
Published: BMC 2011-05-01
Series:Journal of Cardiothoracic Surgery
Online Access:http://www.cardiothoracicsurgery.org/content/6/1/69