A rare BCR-ABL1 transcript in Philadelphia-positive acute myeloid leukemia: case report and literature review

A rare BCR-ABL1 transcript in Philadelphia-positive acute myeloid leukemia: case report and literature review

Abstract Background Philadelphia (Ph) chromosome results from the reciprocal translocation t(9;22)(q34.1;q11.2) and is diagnostic for chronic myeloid leukemia (CML). However, this translocation is also found in acute lymphoid leukemia (ALL), as well as in rare cases of acute myeloid leukemias (AML)....

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Bibliographic Details
Main Authors: Monica Piedimonte, Tiziana Ottone, Valentina Alfonso, Antonella Ferrari, Esmeralda Conte, Mariadomenica Divona, Maria Paola Bianchi, Maria Rosaria Ricciardi, Simone Mirabilii, Roberto Licchetta, Alessia Campagna, Laura Cicconi, Giulia Galassi, Sabrina Pelliccia, Annapaola Leporace, Francesco Lo Coco, Agostino Tafuri
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Cancer
Subjects:
Acute myeloid leukemia
Philadelphia chromosome
BCR-ABL1 e6a2
Atypical transcripts
TKI
Online Access:http://link.springer.com/article/10.1186/s12885-019-5265-5

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http://link.springer.com/article/10.1186/s12885-019-5265-5

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