In Vitro and In Vivo Effects of SerpinA1 on the Modulation of Transthyretin Proteolysis
Transthyretin (TTR) proteolysis has been recognized as a complementary mechanism contributing to transthyretin-related amyloidosis (ATTR amyloidosis). Accordingly, amyloid deposits can be composed mainly of full-length TTR or contain a mixture of both cleaved and full-length TTR, particularly in the...
Main Authors: | Filipa Bezerra, Christoph Niemietz, Hartmut H. J. Schmidt, Andree Zibert, Shuling Guo, Brett P. Monia, Paula Gonçalves, Maria João Saraiva, Maria Rosário Almeida |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-08-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/22/17/9488 |
Similar Items
-
Oligomerization Profile of Human Transthyretin Variants with Distinct Amyloidogenicity
by: Ana Frangolho, et al.
Published: (2020-12-01) -
Selection of transthyretin amyloid inhibitors
by: Iakovleva, Irina
Published: (2016) -
A Clinical Case of the Hereditary Transthyretin Amyloidosis
by: E. V. Reznik, et al.
Published: (2021-05-01) -
The role of non-coding genetic variants on transthyretin gene transcription in transthyretin amyloidosis
by: Boldbaatar, Batbold
Published: (2021) -
Hereditary transthyretin amyloidosis
by: T. A. Adyan, et al.
Published: (2020-01-01)