Aberrant methylation of the M-type phospholipase A<sub>2</sub> receptor gene in leukemic cells

Aberrant methylation of the M-type phospholipase A<sub>2</sub> receptor gene in leukemic cells

<p>Abstract</p> <p>Background</p> <p>The M-type phospholipase A2 receptor (PLA2R1) plays a crucial role in several signaling pathways and may act as tumor-suppressor. This study examined the expression and methylation of the <it>PLA2R1</it> gene in Jurkat an...

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Bibliographic Details
Main Authors: Menschikowski Mario, Platzbecker Uwe, Hagelgans Albert, Vogel Margot, Thiede Christian, Schönefeldt Claudia, Lehnert Renate, Eisenhofer Graeme, Siegert Gabriele
Format: Article
Language:English
Published: BMC 2012-12-01
Series:BMC Cancer
Subjects:
Phospholipase A<sub>2</sub> receptor
DNA methylation
High resolution melting analysis
Leukemia
Online Access:http://www.biomedcentral.com/1471-2407/12/576

Internet

http://www.biomedcentral.com/1471-2407/12/576

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