Fish oil protects against corn oil-induced cardiac insulin resistance and left ventricular dysfunction in rats via upregulation of PPAR-β/γ and inhibition of diacylglycerol/PCK axis activation

Fish oil protects against corn oil-induced cardiac insulin resistance and left ventricular dysfunction in rats via upregulation of PPAR-β/γ and inhibition of diacylglycerol/PCK axis activation

This study investigated the effects corn oil (CO) and different ratios of corn oil plus fish oil (FO) on insulin signaling in rat's heart. Adult male rats were fed low (LFD) or isocaloric high-fat diets (HFDs) of CO alone or CO + FO (ratios of 9:1 or 4:1). Cultured cardiomyocytes were treated w...

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Bibliographic Details
Main Authors: Refaat A. Eid, Mubarak Al-Shraim, Samy M. Eleawa, Mohamed Samir Ahmed Zaki, Attalla Farag El-kott, Muhammad Alaa Eldeen, Mahmoud A. Alkhateeb, Mohammed Alassiri, Hussain Alderah
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Journal of Functional Foods
Subjects:
Corn oil
Fish oil
Heart
Insulin
PPARs
Rats
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464619301458

Internet

http://www.sciencedirect.com/science/article/pii/S1756464619301458

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