Reduction of the P5A-ATPase Spf1p phosphoenzyme by a Ca2+-dependent phosphatase.

P5 ATPases are eukaryotic pumps important for cellular metal ion, lipid and protein homeostasis; however, their transported substrate, if any, remains to be identified. Ca2+ was proposed to act as a ligand of P5 ATPases because it decreases the level of phosphoenzyme of the Spf1p P5A ATPase from Sac...

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Bibliographic Details
Main Authors: Gerardo R Corradi, Luciana R Mazzitelli, Guido D Petrovich, Paula Grenon, Danny M Sørensen, Michael Palmgren, Felicitas de Tezanos Pinto, Hugo P Adamo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0232476