Spirulina maxima Extract Ameliorates Learning and Memory Impairments via Inhibiting GSK-3β Phosphorylation Induced by Intracerebroventricular Injection of Amyloid-β 1–42 in Mice

Spirulina maxima Extract Ameliorates Learning and Memory Impairments via Inhibiting GSK-3β Phosphorylation Induced by Intracerebroventricular Injection of Amyloid-β 1–42 in Mice

Spirulina maxima, a microalga containing high levels of protein and many polyphenols, including chlorophyll a and C-phycocyanin, has antioxidant and anti-inflammatory therapeutic effects. However, the mechanisms where by Spirulina maxima ameliorates cognitive disorders induced by amyloid-β 1–42 (Aβ1...

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Bibliographic Details
Main Authors: Eun-Jeong Koh, Kui-Jin Kim, Ji-Hyeon Song, Jia Choi, Hyeon Yong Lee, Do-Hyung Kang, Ho Jin Heo, Boo-Yong Lee
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:International Journal of Molecular Sciences
Subjects:
cognitive impairment
Spirulina maxima 70% ethanol extract (SM70EE)
amyloid precursor protein (APP) processing
oxidative stress
glycogen synthase kinase-3β (GSK-3β)
Online Access:https://www.mdpi.com/1422-0067/18/11/2401

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https://www.mdpi.com/1422-0067/18/11/2401

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