Epigenetic Regulation of S100A9 and S100A12 Expression in Monocyte-Macrophage System in Hyperglycemic Conditions

Epigenetic Regulation of S100A9 and S100A12 Expression in Monocyte-Macrophage System in Hyperglycemic Conditions

The number of diabetic patients in Europe and world-wide is growing. Diabetes confers a 2-fold higher risk for vascular disease. Lack of insulin production (Type 1 diabetes, T1D) or lack of insulin responsiveness (Type 2 diabetes, T2D) causes systemic metabolic changes such as hyperglycemia (HG) whi...

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Bibliographic Details
Main Authors: Dieuwertje M. Mossel, Kondaiah Moganti, Vladimir Riabov, Christel Weiss, Stefan Kopf, Julio Cordero, Gergana Dobreva, Marianne G. Rots, Harald Klüter, Martin C. Harmsen, Julia Kzhyshkowska
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Immunology
Subjects:
diabetes mellitus
inflammation
macrophage
epigenetic
histone code
metabolic memory
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01071/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01071/full

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