Schistosomes induce regulatory features in human and mouse CD1d(hi) B cells: inhibition of allergic inflammation by IL-10 and regulatory T cells.

Schistosomes induce regulatory features in human and mouse CD1d(hi) B cells: inhibition of allergic inflammation by IL-10 and regulatory T cells.

Chronic helminth infections, such as schistosomes, are negatively associated with allergic disorders. Here, using B cell IL-10-deficient mice, Schistosoma mansoni-mediated protection against experimental ovalbumin-induced allergic airway inflammation (AAI) was shown to be specifically dependent on I...

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Bibliographic Details
Main Authors: Luciën E P M van der Vlugt, Lucja A Labuda, Arifa Ozir-Fazalalikhan, Ellen Lievers, Anouk K Gloudemans, Kit-Yeng Liu, Tom A Barr, Tim Sparwasser, Louis Boon, Ulysse Ateba Ngoa, Eliane Ngoune Feugap, Ayola A Adegnika, Peter G Kremsner, David Gray, Maria Yazdanbakhsh, Hermelijn H Smits
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3275567?pdf=render

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http://europepmc.org/articles/PMC3275567?pdf=render

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