Interplay between cytoskeletal stresses and cell adaptation under chronic flow.

Using stress sensitive FRET sensors we have measured cytoskeletal stresses in α-actinin and the associated reorganization of the actin cytoskeleton in cells subjected to chronic shear stress. We show that long-term shear stress reduces the average actinin stress and this effect is reversible with re...

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Bibliographic Details
Main Authors: Deepika Verma, Nannan Ye, Fanjie Meng, Frederick Sachs, Jason Rahimzadeh, Susan Z Hua
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3446919?pdf=render