Total Synthesis of (-)-(7S,10R)-Calamenene and (-)-(7S,10R)-2-Hydroxycalamenene by Use of a Ring-Closing Metathesis Reaction. A Comparison of the cis- and trans-Isomers

Total Synthesis of (-)-(7S,10R)-Calamenene and (-)-(7S,10R)-2-Hydroxycalamenene by Use of a Ring-Closing Metathesis Reaction. A Comparison of the cis- and trans-Isomers

The title compounds have been synthesized starting from l-menthone by application of a ring-closing metathesis reaction to confirm their reported absolute and relative stereochemistry. Comparisons of the NMR spectra and specific rotations are also discussed.

Bibliographic Details
Main Authors: Yoshinori Asakawa, Fumihiro Nagashima, Motoo Tori, Masakazu Sono, Masashi Imoto, Katsuyuki Nakashima
Format: Article
Language:English
Published: MDPI AG 2002-07-01
Series:Molecules
Subjects:
Calamenene
hydroxycalamenene
ring closing metathesis
absolute configuration
sesquiterpene
Online Access:http://www.mdpi.com/1420-3049/7/7/517/

Internet

http://www.mdpi.com/1420-3049/7/7/517/

Similar Items