Detection of immunogenic cell death and its relevance for cancer therapy

Abstract Chemotherapy, radiation therapy, as well as targeted anticancer agents can induce clinically relevant tumor-targeting immune responses, which critically rely on the antigenicity of malignant cells and their capacity to generate adjuvant signals. In particular, immunogenic cell death (ICD) i...

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Bibliographic Details
Main Authors: Jitka Fucikova, Oliver Kepp, Lenka Kasikova, Giulia Petroni, Takahiro Yamazaki, Peng Liu, Liwei Zhao, Radek Spisek, Guido Kroemer, Lorenzo Galluzzi
Format: Article
Language:English
Published: Nature Publishing Group 2020-11-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-020-03221-2