Inhibition Effect of Chloroquine and Integrin-Linked Kinase Knockdown on Translation in Melanoma Cells

Inhibition Effect of Chloroquine and Integrin-Linked Kinase Knockdown on Translation in Melanoma Cells

The twofold role of autophagy in cancer is often the therapeutic target. Numerous regulatory pathways are shared between autophagy and other molecular processes needed in tumorigenesis, such as translation or survival signaling. Thus, we have assumed that ILK knockdown should promote autophagy, and...

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Bibliographic Details
Main Authors: Dorota Gil, Piotr Laidler, Marta Zarzycka, Joanna Dulińska-Litewka
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
ILK
chloroquine
mTOR
AMPK
melanoma
eIF4E
Online Access:https://www.mdpi.com/1422-0067/22/7/3682

Internet

https://www.mdpi.com/1422-0067/22/7/3682

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