Condensation of Plasmid DNA Enhances Mitochondrial Association in Skeletal Muscle Following Hydrodynamic Limb Vein Injection

Mitochondrial gene therapy and diagnosis have the potential to provide substantial medical benefits. However, the utility of this approach has not yet been realized because the technology available for mitochondrial gene delivery continues to be a bottleneck. We previously reported on mitochondrial...

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Bibliographic Details
Main Authors: Yukari Yasuzaki, Yuma Yamada, Yutaka Fukuda, Hideyoshi Harashima
Format: Article
Language:English
Published: MDPI AG 2014-08-01
Series:Pharmaceuticals
Subjects:
Online Access:http://www.mdpi.com/1424-8247/7/8/881