Chitosan-Collagen 3D Matrix Mimics Trabecular Bone and Regulates RANKL-Mediated Paracrine Cues of Differentiated Osteoblast and Mesenchymal Stem Cells for Bone Marrow Macrophage-Derived Osteoclastogenesis
Recent studies have identified the regulatory mechanism of collagen in bone ossification and resorption. Due to its excellent bio-mimicry property, collagen is used for the treatment of several bone and joint disease such as arthritis, osteoporosis, and osteopenia. In bone, the biological action of...
Main Authors: | Jeevithan Elango, Kandasamy Saravanakumar, Saeed Ur Rahman, Yves Henrotin, Joe M. Regenstein, Wenhui Wu, Bin Bao |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-05-01
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Series: | Biomolecules |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-273X/9/5/173 |
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