Marine Bacterial Aromatic Polyketides From Host-Dependent Heterologous Expression and Fungal Mode of Cyclization

Marine Bacterial Aromatic Polyketides From Host-Dependent Heterologous Expression and Fungal Mode of Cyclization

The structure diversity of type II polyketide synthases-derived bacterial aromatic polyketides is often enhanced by enzyme controlled or spontaneous cyclizations. Here we report the discovery of bacterial aromatic polyketides generated from 5 different cyclization modes and pathway crosstalk between...

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Bibliographic Details
Main Authors: Chunshuai Huang, Chunfang Yang, Yiguang Zhu, Wenjun Zhang, Chengshan Yuan, Changsheng Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Chemistry
Subjects:
heterologous expression
aromatic polyketides
type II polyketide synthase
cyclization modes
pathway crosstalk
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2018.00528/full

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https://www.frontiersin.org/article/10.3389/fchem.2018.00528/full

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