Long-range Transcriptome Sequencing Reveals Cancer Cell Growth Regulatory Chimeric mRNA

mRNA chimeras from chromosomal translocations often play a role as transforming oncogenes. However, cancer transcriptomes also contain mRNA chimeras that may play a role in tumor development, which arise as transcriptional or post-transcriptional events. To identify such chimeras, we developed a de...

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Bibliographic Details
Main Authors: Roberto Plebani, Gavin R Oliver, Marco Trerotola, Emanuela Guerra, Pamela Cantanelli, Luana Apicella, Andrew Emerson, Alessandro Albiero, Paul D Harkin, Richard D Kennedy, Saverio Alberti
Format: Article
Language:English
Published: Elsevier 2012-11-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558612801205