Host cystathionine-γ lyase derived hydrogen sulfide protects against Pseudomonas aeruginosa sepsis.

Host cystathionine-γ lyase derived hydrogen sulfide protects against Pseudomonas aeruginosa sepsis.

Hydrogen sulfide (H2S) has recently been recognized as a novel gaseous transmitter with several anti-inflammatory properties. The role of host- derived H2S in infections by Pseudomonas aeruginosa was investigated in clinical and mouse models. H2S concentrations and survival was assessed in septic pa...

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Bibliographic Details
Main Authors: Georgios Renieris, Dionysia-Eirini Droggiti, Konstantina Katrini, Panagiotis Koufargyris, Theologia Gkavogianni, Eleni Karakike, Nikolaos Antonakos, Georgia Damoraki, Athanasios Karageorgos, Labros Sabracos, Antonia Katsouda, Elisa Jentho, Sebastian Weis, Rui Wang, Michael Bauer, Csaba Szabo, Kalliopi Platoni, Vasilios Kouloulias, Andreas Papapetropoulos, Evangelos J Giamarellos-Bourboulis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-03-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009473

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https://doi.org/10.1371/journal.ppat.1009473

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