Mendelian randomization study of maternal influences on birthweight and future cardiometabolic risk in the HUNT cohort

Observationally, lower birthweight is a risk factor for cardiometabolic disease. Using Mendelian Randomization, the authors investigate whether maternal genetic factors that lower offspring birthweight also increase offspring cardiometabolic risk and show that the observational correlation is unlike...

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Bibliographic Details
Main Authors: Gunn-Helen Moen, Ben Brumpton, Cristen Willer, Bjørn Olav Åsvold, Kåre I. Birkeland, Geng Wang, Michael C. Neale, Rachel M. Freathy, George Davey Smith, Deborah A. Lawlor, Robert M. Kirkpatrick, Nicole M. Warrington, David M. Evans
Format: Article
Language:English
Published: Nature Publishing Group 2020-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-19257-z