3-Amino-1,2,4-Triazole Induces Quick and Strong Fat Loss in Mice with High Fat-Induced Metabolic Syndrome

Background. Obesity is a growing epidemic with limited effective treatments and an important risk factor for several diseases such as metabolic syndrome (MetS). In this study, we aimed to investigate the effect of 3-amino-1,2,4-triazole (ATZ), an inhibitor of catalase and heme synthesis, in a murine...

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Main Authors: Valéria Nunes-Souza, Nelson Miguel Dias-Júnior, Marcos Antônio Eleutério-Silva, Vanessa P. Ferreira-Neves, Fabiana Andréa Moura, Natalia Alenina, Michael Bader, Luíza A. Rabelo
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2020/3025361