Granule Cell Dispersion in Human Temporal Lobe Epilepsy: Proteomics Investigation of Neurodevelopmental Migratory Pathways

Granule cell dispersion (GCD) is a common pathological feature observed in the hippocampus of patients with Mesial Temporal Lobe Epilepsy (MTLE). Pathomechanisms underlying GCD remain to be elucidated, but one hypothesis proposes aberrant reactivation of neurodevelopmental migratory pathways, possib...

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Bibliographic Details
Main Authors: Joan Y. W. Liu, Natasha Dzurova, Batoul Al-Kaaby, Kevin Mills, Sanjay M. Sisodiya, Maria Thom
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Cellular Neuroscience
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Online Access:https://www.frontiersin.org/article/10.3389/fncel.2020.00053/full